Dermorphin
A heptapeptide from frog skin that is 30 to 40 times stronger than morphine at the mu-opioid receptor. Listed for completeness; the abuse risk is real.
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Orders typically arrive within 3 weeks.
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About
Dermorphin is a μ-opioid receptor agonist originally isolated from the skin of South American Phyllomedusa frogs. It contains a D-alanine residue at position 2, unusual for a vertebrate peptide, which protects it from peptidase breakdown and contributes to its extreme potency.
Read the full research guideWhy people choose it
- Potent analgesia at very low doses (the only reason it has any research interest at all)
- Limited CNS penetration in some animal studies. Research interest in peripheral analgesia without central addiction signal, not yet borne out in humans
- Resistance to enzymatic degradation, giving a longer duration than endogenous opioid peptides
- Of clinical interest as a template for designing safer mu-agonists, not as a drug itself
At a glance
- Experience level
- Advanced
- Administration
- Subcutaneous
Sold for laboratory research only. Not for human consumption. No therapeutic claims are made.
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Dermorphin
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