What dose does this TB-500 calculator use by default?

It starts from the first supported mg/mcg protocol in the MeinePeptide monograph, preferring beginner, then standard, then advanced protocols.

How much bacteriostatic water should I compare?

The chart compares 1 ml, 2 ml, and 3 ml because these are common reconstitution volumes. The interactive calculator lets you enter any volume.

How is TB-500 different from Thymosin Beta-4?

TB-500 is the synthetic active fragment (17 amino acids) corresponding to the cell-binding region of full-length Thymosin Beta-4 (43 amino acids). The shorter peptide is easier to manufacture and is what's actually sold; biologically it appears to replicate the parent protein's repair effects in animal models.

Why the lethargy in the first week?

Best guess: the body redirects metabolic resources toward repair processes that the peptide amplifies. The effect is dose-dependent and time-limited — almost everyone reports it fading by the end of the second week. If lethargy persists past week 2, lower the dose or pause.

Back to TB-500Peptide-specific calculator

TB-500 dosage calculator

Calculate TB-500 concentration, syringe units, doses per vial, and vial longevity from the protocol data.

Target dose per injection: 2 mgFrequency: Twice weeklyStatic chart: 5 mg vial

The chart is educational math only. Use clinician-directed instructions for real treatment decisions.

Prefilled calculator

Reconstitution & dosage calculator

Use the prefilled calculator for the current protocol, then compare common bacteriostatic-water volumes in the static chart below.

Peptide

Peptide quantity (mg)

Bacteriostatic water (ml)

Target dose per injection

Unit

Frequency

Syringe size

Concentration

2.5 mg/ml

Units to draw per dose80

ml per dose0.8 ml

Doses per vial2.5

Days a vial lasts9

Syringe

Fill to 80 units on a 1 ml syringe.

Static chart: 5 mg vial

Reconstitution chart

Common bacteriostatic-water options for the starting protocol.

Bacteriostatic water (ml)	Concentration	Units to draw per dose	ml per dose	Doses per vial	Days a vial lasts
1 ml	5 mg/ml	40	0.4 ml	2.5	17.5
2 ml	2.5 mg/ml	80	0.8 ml	2.5	17.5
3 ml	1.667 mg/ml	120	1.2 ml	2.5	17.5

Protocol table

Advanced

10 mg

twice weekly

Routesubcut

Injection timing6 weeks on / 8 weeks off

Beginner

2 mg

twice weekly

Routesubcut

Injection timing4 weeks on / 4 weeks off

Standard

5 mg

twice weekly

Routesubcut

Injection timing6 weeks on / 6 weeks off

Safety summary

Contraindications

Active cancer or recent cancer history — angiogenesis and cell migration are the exact mechanisms a tumour would benefit from
Pregnancy or breastfeeding
Recent major surgery without clearance from the operating clinician
Caution with anticoagulants given the angiogenic component

Side effects

mildLethargy in the first week — the body redirecting metabolic energy toward repair. Resolves on its own.
mildHeadache or generalised muscle ache during loading, similar to a mild flu day.
mildInjection-site reaction — small bump for under 24 hours.
moderateLong-term human safety data is essentially absent. Decades of grey-market use without major signal, but 'no signal yet' is not 'safe long-term'.

TB-500

A synthetic fragment of Thymosin Beta-4 used for systemic tissue repair. Sister peptide to BPC-157, but where BPC works locally, TB-500 spreads.

Read full monograph