What dose does this Melanotan-2 calculator use by default?

It starts from the first supported mg/mcg protocol in the MeinePeptide monograph, preferring beginner, then standard, then advanced protocols.

How much bacteriostatic water should I compare?

The chart compares 1 ml, 2 ml, and 3 ml because these are common reconstitution volumes. The interactive calculator lets you enter any volume.

Why does it cause erections?

MT-2 activates MC4R in the central nervous system, which drives sexual desire and erection. It's the same mechanism PT-141 uses, but MT-2 isn't selective so you also get the MC1R (tanning) and MC3R effects in the same molecule.

Is the melanoma risk real?

There are case reports of melanoma developing in pre-existing moles during MT-2 use. The biological plausibility (melanocyte stimulation) exists. Formal causation hasn't been established because there are no large prospective trials, and there won't be. Treat it as a risk that the absence of proof doesn't disprove.

Back to Melanotan-2Peptide-specific calculator

Melanotan-2 dosage calculator

Calculate Melanotan-2 concentration, syringe units, doses per vial, and vial longevity from the protocol data.

Target dose per injection: 250 mcgFrequency: DailyStatic chart: 5 mg vial

The chart is educational math only. Use clinician-directed instructions for real treatment decisions.

Prefilled calculator

Reconstitution & dosage calculator

Use the prefilled calculator for the current protocol, then compare common bacteriostatic-water volumes in the static chart below.

Peptide

Peptide quantity (mg)

Bacteriostatic water (ml)

Target dose per injection

Unit

Frequency

Syringe size

Concentration

2.5 mg/ml

Units to draw per dose10

ml per dose0.1 ml

Doses per vial20

Days a vial lasts20

Syringe

Fill to 10 units on a 1 ml syringe.

Static chart: 5 mg vial

Reconstitution chart

Common bacteriostatic-water options for the starting protocol.

Bacteriostatic water (ml)	Concentration	Units to draw per dose	ml per dose	Doses per vial	Days a vial lasts
1 ml	5 mg/ml	5	0.05 ml	20	20
2 ml	2.5 mg/ml	10	0.1 ml	20	20
3 ml	1.667 mg/ml	15	0.15 ml	20	20

Protocol table

Advanced

1 mg

every other day, then weekly maintenance

Routesubcut

Injection timing4 weeks on / 8 weeks off

Beginner

250 mcg

daily for 7 days

Routesubcut

Injection timing1 weeks on / 4 weeks off

Standard

500 mcg

daily for 10 days

Routesubcut

Injection timing2 weeks on / 6 weeks off

Safety summary

Contraindications

Any history of melanoma or many atypical naevi — the mole signal is too high a risk against a cosmetic benefit
Sickle cell disease or other conditions predisposing to priapism
Pregnancy or breastfeeding
Concurrent use of erectogenic drugs (sildenafil, tadalafil) — additive priapism risk
Children, adolescents, and anyone whose skin hasn't been surveyed by a dermatologist recently

Side effects

moderateNausea, sometimes severe, especially in the first week. Worse than MT-1.
moderateSpontaneous erections — uncomfortable, predictable, and at the higher end can become priapism (sustained erection over 4 hours), which is a urological emergency.
moderateMole darkening and new naevi formation, with case reports of melanoma emerging in pre-existing moles during MT-2 use. Causation is debated; the temporal correlation is documented.
mildAppetite suppression — usually welcome, occasionally to a worrying degree.
moderateNo long-term human safety data; the grey-market track record is long but not systematically monitored.

Melanotan-2

The unregulated tanning peptide. Cheaper and more effective on libido than MT-1, but the side effect profile and mole-change risk make this the riskier of the two.

Read full monograph